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Philipp C Kohler Selected Research

queuine tRNA-ribosyltransferase

9/2013High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization.
12/2009How to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylase.
10/2009High-affinity inhibitors of tRNA-guanine transglycosylase replacing the function of a structural water cluster.

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Philipp C Kohler Research Topics

Disease

4Bacillary Dysentery (Shigellosis)
09/2013 - 10/2009
2Foodborne Diseases
09/2013 - 07/2012

Drug/Important Bio-Agent (IBA)

3queuine tRNA-ribosyltransferaseIBA
09/2013 - 10/2009
2EnzymesIBA
09/2013 - 10/2009
2Transfer RNA (tRNA)IBA
09/2013 - 10/2009
1Pharmaceutical PreparationsIBA
09/2013
1Shiga Toxin (Shigella Toxin)IBA
07/2012